Molecular and Cellular Biology  -  BIOS 1500

Fall, 0000

Department of Biological Sciences

Western Michigan University


Laboratory component of this course is partially supported by a grant from National Science Foundation





Instructor:                            Dr. K. Essani

                                                Office: Wood Hall Room 3931 ;  Laboratory: Haenicke Hall Room 2007

                                                Phone: 387-5636; Fax: 387-2849; Email:


Office Hours:                       Tuesdays 2:30-4:00 pm and Thursdays 2:00-4:00 pm


Time and Place:                   Lectures: Mondays, Wednesdays and Fridays,  8:00-8:50 am

                                                Schneider Hall (Haworth Business College) 2000


                                                Laboratory: Day and Time (check your course call number)

                                                Wood Hall 0000


Credit Hours:                       4.0


Text:                                       Biology:  Neil Campbell, 4th. Edition, 1996

                                                The Benjamin/Cummings Publishing Co., Inc.


This course is intended to introduce undergraduate students to cellular and molecular concepts in the biology and biochemistry of cells. The purpose of the text is to provide students with some conceptual background to help comprehend lectures.  The text contains a number of factual errors and omissions. Emphasis should, therefore, be placed on lectures and readings. A general knowledge of protein and nucleic acid biochemistry, at least at the present high school level, will be useful to understand lectures and suggested readings.


Exams and Scoring:                A total of 325 points with five scoring opportunities as follows:



First Exam
50 points
Second Exam
50 points
Third Exam
50 points
Final Exam
75 points
Laboratory Reports & Quizzes
100 points



The FINAL  [COMPREHENSIVE] EXAM will be constructed as follows:  25 points from lectures covered in three previous exams [some questions may be from previous exams], and 50 points from lectures since third exam.  Some questions from GLOSSARY (pages G-1 to G-22) will also be included in the final exam.


Total numerical grade obtained by summing all scoring opportunities will translate into letter grade as follows:


                                90-100% = A,        85-89% = BA,      79-84 %=B,      72-78%= CB.         

                                65-71% = C,         57-64% = DC,      50-56% = D,         0-49%  = E.


Make-up Exams and Quizzes:       


Any make-up exam will be by special arrangements only, and will require written documentation for an excused absence. Make-up exams will be held during the last week of classes (as indicated below) and only approved excused absences are eligible for make-up exams.


Lecture Attendance:


Most of the lectures include some material(s), not covered in the text book and included in exams. Attendance is therefore required.


Laboratory Attendance:


Laboratory attendance is required. Laboratory reports are due within the first 15 minutes of the lab session. Unless your laboratory Teaching Assistant is notified prior to the laboratory session and a LEGITIMATE excuse is presented, quizzes cannot be taken and reports will not be accepted.


Academic Honesty:


Academic ethical standards regarding cheating, fabrication, plagiarism, facilitating academic dishonesty and consequences of these actions are all described in the WMU Undergraduate Catalog. Students sometimes do not understand the definitions of academic standards (e.g. plagiarism) and unwittingly are party to improper conduct. Thus it is important to familiarize yourself with this part of the written definitions described above. Reading these regulations is strongly recommended.

Meeting # & Date


1. General Introduction  
2. Biology Today  
3. Proteins  
4. Nucleic Acids  
5. Emzymes  
6. Light and Electron Microscope  
7. Bacteria and Viruses  
8. Types of Cells  
9. Ribosomes and Endoplasmic Reticulum  
10. Golgi Apparatus and Lysosomes  
11. 1st. Exam  
12. Microbodies and Mitochondria  


14. Cell Wall  
15. Membrane I  
16. Membrane II  
17. Biochemical Energy  
18. Photosynthesis  
19. Cell Cycle and Cancer  
20. Meiosis  
21. 2nd Exam.  
22. Chromosomal Basis of Inheritance  
23. Molecular Basis of Inheritance  
24. Structure and Replication of DNA  
25. Protein Synthesis (Transcription)  
26. Protein Sythesis (Translation)  
27. Animal and Plant Viruses  
28. Conjugation and Plasmids  
29. Genome Organization  
30. 3rd Exam.  
31. Cellular Differentiation and Gene Expression  
32. Gene Expression and Cancer  
33. Recombinant DNA technology I  
34. Recombinant DNA technology II  
35. Trangenic Animal Technology /Gene Therapy  
36. Immunology I  
37. Immunology II  
38. AIDS at Molecular and Cellular Level  
40. Final [Comprehensive] Exam.