tanapox

Laboratory of Virology
Department of Biological Sciences
Western Michigan University
Kalamazoo, MI 49008-5410

Office:(269) 387-5636
Fax:(269) 387-5609
Lab:(269) 387-2661

karim.essani@wmich.edu

Karim Essani, Ph.D.

Professor

Representative publications

  1. Essani, K. and S. Dales. 1979. Biogenesis of vaccinia: Evidence for more than 100 polypeptides in the virion. Virology 95: 385-394.
  2. McFadden, G., K. Essani and S. Dales. 1980. A new endonuclease restriction site which is at the locus of temperature-sensitive mutation in vaccinia virus is associated with true and pseudoreversion. Virology 101: 277-280.
  3. Flintoff, W.F. and K. Essani. 1980. Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate. Biochemistry 19: 4321-4327.
  4. Strejan, G.H., K. Essani and D. Surlan. 1981. Naturally occurring antibodies to liposomes. II. Specificity and electrophoretic pattern of rabbit antibodies reacting with sphingomyelin-containing liposomes.     J. Immunol. 127: 160-165.
  5. Flintoff, W.F., M.K. Weber, C.R. Nagainis, K. Essani, D. Robertson and W. Salser. 1982. Overproduction of dihydrofolate reductase and gene amplification in methotrexate- resistant Chinese hamster ovary cells. Mol. Cell. Biol. 2: 275-285.
  6. Essani, K., R. Dugre and S. Dales. 1982. Involvement of spicules of the envelope during virion assembly examined by means of conditional-lethal mutants and serology. Virology 118: 279-292.
  7. Haspel, M.V., T. Onodera, B.S. Prabhakar, P.R. McClintock, K. Essani, U.R. Ray and A.L. Notkins. 1983. Multiple organ-reactive monoclonal antibodies. Nature 307: 73-76.
  8. Essani, K. and S. Dales. 1983. Biogenesis of vaccinia: Analysis by three factor crosses revealed mutual influence on stability of drug-resistance and temperature-sensitivity when both markers occur in some recombinant isolates. Intervirology 20: 101-107.
  9. Satoh, J., K. Essani, P.R. McClintock and A.L. Notkins. 1984. Human multiple organ-reactive monoclonal autoantibody recognizes growth hormone and a 35K protein. J. Clin. Invest. 74: 1526-1531.Essani, K.,
  10. J. Satoh, B.S. Prabhakar, P.R. McClintock and A.L. Notkins. 1985. Anti-idiotypic antibodies against a human multiple organ-reactive autoantibody: Detection of idiotopes in normal individuals and patients with autoimmune disease. J. Clin. Invest. 76: 1649-1656.
  11. Saegusa, J., B.S. Prabhakar, K. Essani, P.R. McClintock and A.L. Notkins. 1986. Monoclonal antibody to Coxsackievirus B4 reacts with myocardium. J. Inf. Dis. 153: 372.
  12. Essani, K., J. Srinivasappa, P.R. McClintock, B.S. Prabhakar and A.L. Notkins. 1986. Multiple organ-reactive IgG antibody induced by an antiidiotypic antibody to a human monoclonal IgM autoantibody. J. Exp. Med. 163: 1355-1360.
  13. Essani, K., R. Goorha and A. Granoff. 1987. Mutation in a DNA-binding protein reveals an association between DNA-methyltransferase activity and a 26,000 dalton polypeptide in frog virus-3 infected cells. Virology 161: 211-216.
  14. Essani. K., R. Goorha and A. Granoff. 1988. An animal virus-induced DNA-methyltransferase. Gene 74: 71-72.
  15. Essani, K. and A. Granoff. 1989. Amphibian and piscine iridoviruses proposal for nomenclature and taxonomy based on molecular and biological properties. Intervirology 30: 187-193.
  16. Willis, D.B., J.P. Thompson, K. Essani and R. Goorha. 1989. Transcription of methylated viral DNA by eukaryotic RNA polymerase II. Cellular Biophys. 15: 97-111.
  17. Willis, D.B., K. Essani, R. Goorha and A. Granoff. 1990. Transcription of a methylated DNA virus. Nucleic Acid Methylation. UCLA Symp. Mol. Cell. Biol. 128: 139-151.
  18. Chambers, T.M., K. Essani and R.G. Webster. 1990. Conditional expression of foreign genes by temperature-sensitive mutants of vaccinia virus. Gene 95: 275-278.
  19. Beisel, K.W., J. Srinivasappa, M.R. Olsen, A.C. Stiff, K. Essani and B.S. Prabhakar. 1990. A neutralizing monoclonal antibody against Coxsackievirus B4 cross reacts with contractile muscle proteins. Microbial Pathogenesis 8: 151-156.
  20. Dy, L.C., S. Chalasani and K. Essani. 1993. Isolation of Escherichia coli mutants lacking methylcytosine-dependent restriction systems for cloning extensively methylated frog virus 3 DNA. Gene 131: 87-91.
  21. Spangler, C.M. and K. Essani. 1994. Expression of integrated and methylated HIV-LTR in human T cells and monkey kidney cells by a frog virus 3 protein. Virology 204: 651-655.
  22. Essani, K., S. Chalasani, R. Eversole, L. Beuving and L. Birmingham. 1994. Multiple anti-cytokine activities secreted from tanapox virus infected cells. Microbial Pathogenesis 17: 347-353.
  23. Paulose, M., B.L. Bennett, A.M. Manning and K. Essani. 1998. Selective inhibition of TNF- induced cell adhesion molecule gene expression by tanapox virus. Microbial Pathogenesis 25: 33-41.
  24. Mediratta, S. and K. Essani. 1999. The replication cycle of tanapox virus in owl monkey kidney cells: One-step growth curve and viral polypeptides. Canadian J. Microbiol.1: 92-96.
  25. Lee, H-J., K. Essani and G. L. Smith, 2001. The genome sequence of yaba-like disease virus, a Yatapoxvirus. Virology 281: 170-192.
  26. Stahlhut, J.K., C.P. Cowan, K. Essani, D.D. Shoemaker and T. Bartman. 2002. Microsatellite markers for the wasp Euodynems foraminulus (Vespidae:Eumenidae). Moleclar Ecology Notes 2: 467-468.
  27. Brunetti, C.R., M. Paulose-Murphy, R. Singh, J. Qin, J. W. Barrett, A. Tardivel, P. Schneider, K. Essani and G. McFadden. 2003. A secreted high-affinity inhibitor of human TNF from Tanapox virus. Proc. Nat. Acad. Sci. (USA) 100: 4831-4836
  28. Tan, W.G.H., T.J. Barkman, V.G. Chinchar and K. Essani. 2004. Comparativegenomic analyses of frog virus 3, type species of the genus Ranavirus (family Iridoviridae). Virology 323: 70-84.
  29. Tan, W.G.H. and K. Essani. 2007. Frog virus 3 induced DNA helicase and endonuclease activities in the cytoplasm of infected cells are associated with ORF 55L. Submitted
  30. Nazarian, S.H., J. W. Barrett, M.M. Stanford, J.B. Johnston, K. Essani and G. McFadden. (2007). Tropism of Tanapox virus infection in primary human cells. Virology. 368: 32-40.
  31. Rahman, M.M., D. Jeng, R. Singh, J. Coughlin, K. Essani and G. McFadden. (2009). Interaction of human TNF and β2-microglobulin with Tanapox virus-encoded TNF inhibitor, TPV-2L. Virology. 386: 462-468
  32. Lee, H.L. and K. Essani. (2010). Susceptibility of human cancer cell lines to tanapoxvirus. The Virol. Open J. 4: 1-6.

Theses Supervised

  1. Tao, C.-T. 1992. M.S. Thesis. Effect of DNA methylation on expression of Epstein-Barr virus early genes. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  2. Chalasani, S. 1993. M.S. Thesis. Evidence for DNA methylation-sensitive transactivator mediated regulation of an Epstein-Barr virus neutralizing antigen. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  3. Neering, S.J. 1993. M.S. Thesis. Complete nucleotide sequence of PstI-L fragment of tanapox virus genomic DNA. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  4. Spangler, C.M. 1994. M.S. Thesis. Expression of integrated and methylated HIV-LTR in human T cells and monkey kidney cells by frog virus 3 infection. Department of Biological Sciences, WesternMichigan University, Kalamazoo, Michigan.
  5. Lopez-Neblina, F. 1995. M.S. Thesis. The role of nitric oxide in leukocyte-endothelial cell interactions during ischemia and reperfusion. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  6. Mediratta, S. 1997. M.S. Thesis. The replication cycle of tanapox virus in owl monkey kidney cells: One-step growth curve and viral polypeptides. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  7. Shimamura, T. 1997. M.S. Thesis. Characterization of swinepox virus Secretory proteins. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  8. Paulose-Murphy, Mini. 2000. Ph.D. Thesis. Molecular and biological characterization of a tanapox virus TNF-binding protein and complete nucleotide sequence of the PstI-J genomic fragment. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  9. Garimella, Bina. 2000. M.S. Thesis. Role of dopamine D4 receptor in the genomic and Behavioral effects of psychostimulants: Relevance to schizophrenia. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  10. Haller, Scott. 2001. M.S. Thesis. Development and characterization of monoclonal antibodies directed against yaba-like disease virus. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  11. Michael Franz. 2004. M.S. Thesis. Development and characterization of monoclonal antibodies directed against Tanapoxvirus. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  12. Wendy G. H. Tan. 2006. Ph.D. Thesis. Comparative Genomic Analyses and Expression of a Set of Overlapping Open Reading Frames of Frog Virus 3, type species of Ranavirus (Family Irodoviridae). Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  13. Hui Lin Lee. 2009. M.S. Thesis. Evaluation of the oncolytic potential of wild-type tanapoxvirus and its plaque variants. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan.
  14. David Jeng. 2010. Sequential interactions of a tanapoxvirus protein with human β2-microglobulin and α2-macroglobulin. Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan