Lecture Schedule: Human Physiology: BIOS 350
Lectures are given Monday and Wednesday each week from 2:00 - 3:50 pm in Room # 1710 Wood Hall.
Course Instructors: John Spitsbergen, Ph.D.
Department of Biological Sciences
John Jellies, Ph.D.
Department of Biological Sciences
Phone: (387-5623), email:
Textbook: Sherwood, Human Physiology 5th Ed., Brooks/Cole
Course Description: An introduction to the functions and interrelationships of the human body organ systems with a description of various physiological malfunctions. The laboratory provides experience with some types of clinical measurements, laboratory instrumentation, data organization and scientific writing. This course is approved as a writing-intensive course and fulfills the baccalaureate-level writing requirement of the student's curriculum. Prerequisites: Junior or senior standing, BIOS 250 and CHEM 370 and 371. Human Anatomy, BIOS 211, is recommended.
Broad Goals of BIOS 350: Students will develop understanding of the function of the body's organ systems and their roles in the maintenance of homeostasis.
Academic Honesty: You are responsible for making yourself aware of and understanding the policies and procedures in the Undergraduate (pp. 274-276) [Graduate (pp. 25-27)] Catalog that pertain to Academic Honesty. These policies include cheating, fabrication, falsification and forgery, multiple submission, plagiarism, complicity and computer misuse. If there is reason to believe you have been involved in academic dishonesty, you will be referred to the Office of Student Conduct. You will be given the opportunity to review the charge(s). If you believe you are not responsible, you will have the opportunity for a hearing. You should consult with me if you are uncertain about an issue of academic honesty prior to the submission of an assignment or test.
Office hours for Dr. Spitsbergen: Wednesday and Thursday between 10:30-11:30 in Room # 3022 Haenicke Hall. If times are not convenient, individual appointments can be made by directly contacting Dr. Spitsbergen.
Office hours for Dr. Jellies: Wednesday and Thursday between 10:30-11:30 in Room # 3060 Haenicke Hall. If times are not convenient, individual appointments can be made by directly contacting Dr. Jellies.
Point Overview for class:
Lecture Item point value Total points
6 short exams: (5 exams count towards grade, 1 exam will be dropped). Each exam = 80 points.
80 X 5 400
comprehensive final exam 300 300
3 puzzlers 30 X 3 90
Term paper outline 50 50
Final term paper 100 100
Total Lecture Points 940 (61%)
2 exams (not comprehensive) 140 X 2 280
11 lab reports 20 X 11 220
9 Pre-lab quizzes 10 X 9 90
Clean up assignment 10 10
Total Lab Points 600 (39%)
Total points possible: 1540
Final grade assignments:
Percentage of points Grade
59 and below E
All scores of XX.5 and above will be rounded up.
Day Date Topic Sherwood, 5th ed.
John Spitsbergen, Ph.D.
Wed. 1/11/06 Organization of course
Introduction to physiology pp. 1-21
Mon. 1/16 No Class!! MLK Day
Wed. 1/18 Plasma membrane and structure pp. 57-87
Labs start this week!
Mon. 1/23 Generation of membrane potential pp. 87-97
Puzzler #1 handed out, due 2/8
Wed. 1/25 Electrical signals: Graded and pp. 99-117
Mon. 1/30 Synapses and neural transmission pp. 117-131
Lecture exam #1 (40 - 2 pt. questions. Total of 80 points)
(covering lectures 1/11, 1/18, 1/23, 1/25)
Wed. 2/1 Central nervous system organization pp. 133-177
Somatic reflex arc pp. 177-183
Mon. 2/6 Autonomic nervous system pp. 237-245
Wed. 2/8 Neuromuscular junction pp. 246-255
Puzzler #1 due at beginning of class
Mon. 2/13 Muscle contraction pp. 257-268
Lecture exam #2 (40 - 2 pt. questions. Total of 80 points)
(covering lectures 1/30, 2/1, 2/6, 2/8)
Wed. 2/15 Skeletal muscle mechanics pp. 269-276
Muscle metabolism pp. 277-288
Puzzler #2 handed out, due 3/13
Mon. 2/20 Smooth and cardiac muscle physiology pp. 288-301
Wed. 2/22 Cardiac physiology pp. 303-341
Mon. 2/27 Spring Break
Wed. 3/1 Spring Break
John Jellies, Ph.D.
Mon. 3/6 Blood vessels from arteries to capillaries pp. 343-369
Lecture Exam #3 (40 - 2 pt. questions. Total of 80 points)
(covering lectures from 2/13, 2/15, 2/20, 2/22)
Wed. 3/8 Veins and blood pressure pp. 370-389
Mon. 3/13 Respiratory system pp. 459-483
Puzzler #2 due at beginning of class
Wed. 3/15 Gas exchange and transport pp. 483-509
Mon. 3/20 The urinary system: reabsorption, pp. 511-537
secretion and filtration
Lecture Exam #4 (40 - 2 pt. questions. Total of 80 points)
(covering lectures from 3/6, 3/8, 3/13, 3/15)
Wed. 3/22 Urine excretion and renal hormones pp. 537-557
Mon. 3/27 GI physiology; upper digestive system pp. 591-615
Wed. 3/29 GI physiology, digestion and absorption pp. 615-645
Puzzler #3 handed out, due 4/10
Mon. 4/3 General principles of endocrinology pp. 667-699
Lecture Exam #5 (40 - 2 pt. questions. Total of 80 points)
(covering lectures from 3/20, 3/22, 3/27, 3/29)
Wed. 4/5 Peripheral endocrine glands pp. 701-733
Final Term paper due at beginning of class
Mon. 4/10 Male reproductive physiology pp. 749-770
Puzzler #3 due at beginning of class
Wed. 4/12 Female reproductive physiology pp. 770-781
Lecture Exam #6 (40 - 2 pt. questions)
(covering lectures from 4/3, 4/5, 4/10)
Mon. 4/17 Pregnancy Physiology! pp. 781-802
Wed. 4/19 Mystery Lecture.
Mon. 4/24 Final Exam 2:45 4:45 PM.
The final exam will be cumulative but weighted heavier on questions concerning female reproductive physiology and pregnancy. The final exam will be given Monday, April 24th, 2006 from 2:45 4:45 pm. It will consist of 100 - 2 pt. multiple choice questions and 4 - 25 pt. essay questions (each can be answered in a paragraph) for a total of 300 points.
FINAL EXAM ESSAY QUESTIONS:
4 essay questions will be selected by Drs. Spitsbergen and Jellies from the following choice of 10. The answers to all questions can be found in Sherwood's "Human Physiology" fifth edition. All questions are obtained from "Points to Ponder."
1. Considering the nature of negative-feedback control and the function of the respiratory system, what effect do you predict that a decrease in C02 in the internal environment would have on how rapidly and deeply a person breathes? Points to ponder: pg 20 #1.
2. Beck N. was apprehensive as she sat in the dentist's chair awaiting the placement of her first silver amalgam (the "filling" in a cavity in a tooth). Before preparing the tooth for the amalgam by drilling away the decayed portion of the tooth, the dentist injected a local anesthetic in the nerve pathway supplying the region. As a result, Becky, much to her relief, did not feel any pain during the drilling and filling procedure. Local anesthetics block Na+ channels. Explain how this action prevents the transmission of pain impulses to the brain. Points to Ponder: pg. 131 #6.
3. Julio D., who had recently retired, was enjoying an afternoon of playing golf when suddenly he experienced a severe headache and dizziness. These symptoms were quickly followed by numbness and partial paralysis on the upper right side of his body, accompanied by an inability to speak. After being rushed to the emergency room, Julio was diagnosed as having suffered a stroke. Based on the observed neurologic impairment, what areas of his brain were affected? Points to Ponder: pg. 183 #6.
4. Explain why epinephrine, which causes arteriolar constriction (narrowing) in most tissues, is frequently administered in conjunction with local anesthetics. Points to Ponder: pg 155 #1.
5. Through what regulatory mechanisms is a transplanted heart, which does not have any innervation, able to adjust the cardiac output to meet the body's changing needs? Points to Ponder: pg. 340, #4.
6. The long-looped nephrons of animals adapted to survive with minimal water consumption, such as desert rats, have relatively much longer loops of Henle than humans have. Of what benefit would these longer loops be? Points to Ponder: pg. 556, #1.
7. At 18 years of age, 8-foot Anthony O. was diagnosed with gigantism caused by a pituitary tumor. The condition was treated by surgically removing his pituitary gland. What hormonal replacement therapy would Anthony need? Points to Ponder: pg. 699, #6.
8. Why would an infection tend to raise the blood glucose level of a diabetic individual? Points to Ponder: pg. 746, #3.
9. What type of sexual dysfunction might arise in men taking drugs that inhibit sympathetic nervous system activity as part of the treatment for high blood pressure? Points to Ponder: pg. 802, #3.
10. Low on the list of popular animals are vampire bats, leeches and ticks, and yet these animals may someday indirectly save your life. Scientists are currently examining the "saliva" of these blood-sucking creatures in search of new chemicals that might limit cardiac muscle damage in heart attack victims. What do you suspect the nature of these sought-after chemicals is? Points to Ponder: pg. 410 #3.